ea0016p755 | Thyroid | ECE2008
Willhauck Michael
, Kessel Anne
, Klutz Katrin
, Samani Bibi Rana Sharif
, Wunderlich Nathalie
, Gildehaus Franz Josef
, Zach Christian
, Berking Carola
, Vile Richard
, Goke Burkhard
, Spitzweg Christine
In its early stages, malignant melanoma can be cured by surgical resection, but once it has progressed to the metastatic stage it does not respond to current therapies. Therefore, the development of novel treatment strategies, such as gene therapy, is urgently needed. To investigate an alternative approach, we examined the feasibility of NIS-mediated radionuclide therapy (131I, 188Re) of malignant melanoma following human sodium iodide symporter (NIS) gen...